The following transactions were recorded by the Arizona Diamondbacks for the calendar year 2000.
| December | |
| Date | Description |
| 12/21/2000 | Re-signed infielders Craig Counsell and Hanley Frias to one-year contracts. |
| 12/15/2000 | Signed free agent outfielder Midre Cummings, who had been with the Boston Red Sox, to a one-year contract. |
| 12/14/2000 | Signed pitcher Curt Schilling to a three-year contract extension. |
| 12/08/2000 | Signed free agent first baseman Mark Grace, who had been with the Chicago Cubs, to a two-year contract. |
| 12/07/2000 | Signed free agent pitcher Jason Jacome; sold the contract of first baseman Alex Cabrera to the Seibu Lions of the Japanese Pacific League; named Steve Scarsone manager of the South Bend Silver Hawks of the Midwest League (Class A). |
| 12/06/2000 | Signed pitcher Armando Reynoso to a two-year contract; named Bob Welch pitching coach. |
| November | |
| Date | Description |
| 11/30/2000 | Announced the resignation of executive vice president Roland Hemond to become executive advisor to the general manager of the Chicago White Sox. |
| 11/15/2000 | Signed pitcher Miguel Batista; named Eddie Rodriguez first base coach; named Charles Scott west regional scouting director; named Mark Baca, Mike Daughtry, Doug Gassaway and Steve Kmetko scouts. |
| 11/10/2000 | Named first base coach Dwayne Murphy hitting coach. |
| 11/06/2000 | Named Bob Melvin bench coach. |
| 11/02/2000 | Signed catcher Ken Huckaby to a one-year contract and added him to the major league roster. |
| 11/01/2000 | Re-signed pitcher Mike Morgan to a one-year contract; named Chris Speier third base coach. |
| October | |
| Date | Description |
| 10/30/2000 | Named Bob Brenly as manager. |
| 10/19/2000 | Announced the resignation of senior assistant to the general manager Mel Didier. |
| 10/17/2000 | San Diego Padres claimed outfielder Mike Colangelo off waivers from the Arizona Diamondbacks. |
| 10/13/2000 | Signed pitcher Kennie Steenstra and outfielder Chip Sell to minor league contracts for the 2001 season. |
| 10/02/2000 | Fired manager Buck Showalter. |
| September | |
| Date | Description |
| 09/21/2000 | Extended the player development contract with the South Bend Silver Hawks of the Midwest League (A) through the 2004 season. |
| 09/14/2000 | Entered into a player development contract with the Lancaster JetHawks of the California League (A) through the 2004 season. |
| 09/05/2000 | Recalled pitcher Geraldo Guzman and outfielder Jason Conti from Tucson of the Pacific Coast League (AAA). |
| 09/02/2000 | Signed pitcher Tanner Eriksen. |
| 09/01/2000 | Activated pitcher Todd Stottlemyre from the 60-day disabled list and infielder Danny Klassen from the 15-day disabled list; recalled catcher Rod Barajas and from Tucson of the Pacific Coast League (AAA). |
| August | |
| Date | Description |
| 08/31/2000 | Purchased the contract of outfielder Matt Kieske from Tucson of the Pacific Coast League (AAA), optioned outfielder Jason Conti to Tucson. |
| 08/30/2000 | Purchased the contract of pitcher Darren Holmes from Tucson of the Pacific Coast League (AAA). Optioned pitcher Geraldo Guzman to Tucson of the Pacific Coast League (AAA). |
| 08/26/2000 | Promoted first baseman John Egly to South Bend of the Midwest League (A). |
| 08/20/2000 | Placed first baseman Erubiel Durazo on the 15-day disabled list with a right wrist injury; recalled first baseman Alex Carbera from Tucson of the Pacific Coast League (AAA). |
| 08/13/2000 | Placed pitcher Johnny Ruffin on the 15-day disabled list with a strained groin muscle; recalled outfielder David Dellucci from Tucson of the Pacific Coast League (AAA). |
| 08/09/2000 | Optioned first baseman Alex Cabrera and outfielder Rob Ryan to Tucson of the Pacific Coast League (AAA); recalled first baseman Erubiel Durazo and pitcher Byung-Hyun Kim from Tucson of the Pacific Coast League (AAA). |
| 08/01/2000 | Optioned first baseman Erubiel Durazo to Tucson of the Pacific Coast League (AAA); recalled outfielder Jason Conti from Tucson of the Pacific Coast League (AAA). |
| July | |
| Date | Description |
| 07/30/2000 | Optioned pitcher Byung-Hyun Kim to Tucson of the Pacific Coast League (AAA); Purchased the contract of pitcher Johnny Ruffin from Tucson of the Pacific Coast League (AAA). |
| 07/27/2000 | Recalled outfielder Rob Ryan from Tucson of the Pacific Coast League (AAA). |
| 07/26/2000 | Philadelphia Phillies -- Traded pitcher Curt Schilling to the Arizona Diamondbacks for outfielder-first baseman Travis Lee and pitchers Omar Daal, Vicente Padilla and Nelson Figueroa. |
| 07/17/2000 | Optioned pitcher Nelson Figueroa to Tucson of the Pacific Coast League (AAA); recalled pitcher Geraldo Guzman from Tucson of the Pacific Coast League (AAA). Optioned outfielder Jason Conti to Tucson of the Pacific Coast League (AAA); Activated infielder Alex Cabrera from the 15-day disabled list. |
| 07/16/2000 | Optioned outfielder Travis Lee to Tucson of the Pacific Coast League (AAA); recalled pitcher Nelson Figueroa from Tucson of the Pacific Coast League (AAA). |
| 07/13/2000 | Activated infielder Erubiel Durazo from the 15-day disabled list. Activated infielder Matt Williams from the 15-day disabled list. Optioned outfielder Rob Ryan to Tucson of the Pacific Coast League (AAA). Placed infielder Danny Klassen on the 15-day disabled list with an injured right toe. |
| 07/07/2000 | Optioned pitcher Geraldo Guzman to Tucson of the Pacific Coast League (AAA). Recalled outfielder Rob Ryan from Tucson of the Pacific Coast League (AAA). |
| 07/05/2000 | Optioned pitcher Nelson Figueroa to Tucson of the Pacific Coast League (AAA). Recalled pitcher Geraldo Guzman from Tucson of the Pacific Coast League (AAA). |
| 07/03/2000 | Placed infielder Alex Cabrera on the 15-day disabled list with a strained left groin; recalled pitcher Nelson Figueroa from Tucson of the Pacific Coast League (AAA). |
| June | |
| Date | Description |
| 06/29/2000 | Placed first baseman Erubiel Durazo on the 15-day disabled list with soreness of the right wrist retroactive to June 27; recalled outfielder Jason Conti from Tucson of the Pacific Coast League (AAA). Signed free agend outfielder Damon Mashore and assigned him to Tucson. |
| 06/28/2000 | Signed pitcher Bill White. |
| 06/26/2000 | Placed pitcher Todd Stottlemyre on the 15-day disabled list with tendinitis of the right elbow; purchased the contract of first baseman Alex Cabrera from El Paso of the Texas League (AA). |
| 06/25/2000 | Placed infielder Matt Williams on the 15-day disabled list with a pulled right quadraceps muscle. Recalled infielder Danny Klassen from Tucson (AAA) of the Pacific Coast League. |
| 06/24/2000 | Activated infielder Erubiel Durazo from the 15-day disabled list; designated outfielder Bernard Gilkey for assignment. |
| 06/15/2000 | Activated pitcher Todd Stottlemyre from the 15-day disabled list; optioned outfielder Turner Ward to Tucson of the Pacific Coast League (AAA). |
| 06/09/2000 | Traded infielder Andy Fox to the Florida Marlins for outfielder Danny Bautista; signed outfielders Julius Foreman, Steve Woodward and Marques Chilsom and pitchers Gregory Belson, Matthew Steele and Carlton Wells; activated first baseman-outfielder Travis Lee from the 15-day disabled list; optioned infielder Danny Klassen to Tucson of the Pacific Coast League (AAA). |
| 06/08/2000 | Signed catchers John Massey and Craig Ansman, pitcher Joseph Riccardi and infielder Orlando Delvanez. |
| 06/05/2000 | Recalled infielder Danny Klassen from Tucson of the Pacific Coast League (AAA); optioned pitcher Nelson Figueroa to Tucson. |
| 06/02/2000 | Acquired pitcher Bill Pulsipher from the Mets in exchange for infielder-outfielder Lenny Harris. Recalled pitcher Nelson Fugueroa from Tucson of the the Pacific Coast League (AAA). |
| May | |
| Date | Description |
| 05/30/2000 | Placed first baseman Erubiel Durazo on the 15-day disabled list with torn cartilage in his right wrist; recalled infielder Craig Counsell from Tucson of the Pacific Coast League (AAA); released pitcher Doug Kohl and outfielder Justin Graham; assigned outfielder Joel Noboa to extended spring training. |
| 05/29/2000 | Placed pitcher Todd Stottlemyre on the 15 day disabled list with soreness of his right elbow, recalled pitcher Vicente Padilla from Tucson of the Pacific Coast League (AAA). |
| 05/26/2000 | Placed outfielder Travis Lee on the 15-day disabled list retroactive to 05/25/2000 with a pulled right groin muscle; purchased the contract of outfielder Turner Ward of Tucson in the Pacific Coast League (AAA). |
| 05/23/2000 | Activated infielder Matt Williams from the 15-day disabled list; optioned infielder Danny Klassen to Tucson of the Pacific Coast League (AAA). |
| 05/20/2000 | Activated pitcher Matt Mantei from the 15-day disabled list; optioned pitcher Vincente Padilla to Tucson of the Pacific Coast League (AAA). |
| 05/05/2000 | Placed pitcher Matt Mantei on the 15-day disabled list with weakness in his right shoulder. Purchased the contract of pitcher Vicente Padilla from Tucson of the Pacific Coast League (AAA). |
| 05/04/2000 | The St. Louis Cardinals signed free agent pitcher Darren Holmes. |
| April | |
| Date | Description |
| 04/28/2000 | Placed pitcher Darren Holmes on waivers for the purpose of giving him his unconditional release. |
| 04/21/2000 | Activated pitcher Matt Mantei off the 15-day disabled list. Designated pitcher Darren Holmes for assignment. |
| 04/19/2000 | Boston Red Sox acquired outfielder Garry Maddox Jr. from the Arizona Diamondbacks for infielder Javier Fuentes. |
| 04/17/2000 | Activated infielder Andy Fox from the 15-day disabled list. Optioned outfielder David Dellucci to Tucson of the Pacific Coast League (AAA). |
| 04/15/2000 | The Florida Marlins acquired catcher John Pachot from the Arizona Diamondbacks for pitcher Ryan Creek. |
| 04/03/2000 | Optioned pitcher Vicente Padilla to Tucson of the Pacific Coast League (AAA). Waived infielder Luis Ordaz for the purpose of giving him his unconditional release. Assigned pitcher Jim Corsi to Tucson. |
| 04/02/2000 | Placed pitcher Matt Mantei on the 15-day disabled list with right biceps tendinitis. |
| March | |
| Date | Description |
| 03/29/2000 | Pitcher Brad Clontz was put on waivers for the purpose of his unconditional release. |
| 03/29/2000 | Placed infielder Matt Williams on the 15-day disabled list with broken bone in right foot. |
| 03/27/2000 | Optioned catcher Rod Barajas and infielder Danny Klassen to Tucson of the Pacific Coast League (AAA). The Diamondbacks assigned pitcher Erik Sabel to their minor league camp. |
| 03/19/2000 | Optioned pitcher Geraldo Guzman to Tucson of the Pacific Coast League (AAA). The Diamondbacks assigned catcher Ken Huckaby to their minor league camp. |
| 03/17/2000 | Signed infielder Craig Counsell and pitcher Johnny Ruffin to minor league contracts. The Diamondbacks reassigned pitcher Jeremy Ward to their minor league camp. The Arizona Diamondbacks traded infielder Jackie Rexrode to the Chicago White Sox for pitcher Brian Scott. |
| 03/14/2000 | Pitchers John Patterson, Nick Bierbrodt, Stephen Randolph, Nelson Figueroa, and infielder Junior Spivey were reassigned to the minor league camp. |
| 03/11/2000 | Agreed to terms with infielders Hanley Frias, Erubiel Durazo, catcher Damian Miller, and outfielder Travis Lee on one-year contracts. |
| 03/10/2000 | Assigned the following players to their minor league camp: pitchers Jeff Kubenka and Martin Sanchez and catcher John Pachot. Re-assigned outfielder Jason Conti and pitcher Troy Brohawn to the minor league camp to continue their rehabilitation. |
| February | |
| Date | Description |
| 02/29/2000 | Signed pitcher Ben Norris to a one-year contract. |
| 02/24/2000 | Signed pitchers Troy Brohawn and Stephen Randolph and infielder Danny Klassen to one-year contracts. Agreed to terms with catcher Rod Barajas on a one-year contract. |
| 02/20/2000 | Signed outfielder Turner Ward and pitcher Jim Corsi to minor league contracts and invited them to spring training. |
| 02/18/2000 | Released pitcher Al Garcia. |
| 02/17/2000 | Signed pitcher Brad Clontz to a one-year contract. |
| 02/13/2000 | Signed utility man Andy Fox to a one-year contract. |
| 02/07/2000 | Invited pitchers Al Garcia, John Patterson, Erik Sabel, Martin Sanchez, Jeremy Ward Jeff Kubenka and Mike Morgan, first baseman Alex Cabrera, catchers Ken Huckaby and John Pachot to spring training. |
| 02/02/2000 | Released pitcher Bobby Chouinard. |
| January | |
| Date | Description |
| 01/28/2000 | Signed pitcher Brian Anderson to a three-year contract. |
| 01/21/2000 | Named Bobby Dickerson manager at El Paso of the Texas League (AA). |
| 01/14/2000 | Signed pitcher Matt Mantei to a one-year contract. Signed free agent pitcher Mike Morgan, who had been with the Texas Rangers, to a minor-league contract. |
| 01/13/2000 | Named Scott Geyer vice president of broadcasting and Gina Giallonardo director of marketing. |
| 01/07/2000 | Signed free agent pitcher Andy Benes, who had been with the Arizona Diamondbacks, to a three-year contract with a club option for a fourth season. |
| 01/06/2000 | Named Bryan Lambe special assistant to the general manager. |
| 01/05/2000 | The Los Angeles Dodgers signed free agent pitcher Gregg Olson, who had been with the Arizona Diamondbacks, to a two-year contract. |
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